Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ Cdc25 Inhibitor IV, NSC 95397
The Cdc25 Inhibitor IV, NSC 95397, also referenced under CAS 93718-83-3, controls the biological activity of Cdc25. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Amiloride, Hydrochloride
An inhibitor of angiogenesis.
MilliporeSigma™ Calbiochem™ LRRK2 Inhibitor III, HG-10-102-01
A cell-permeable 2,4-diaminopyrimidinyl compound that acts as a potent, ATP-competitive LRRK2-selective inhibitor (IC5050 =
MilliporeSigma™ Calbiochem™ TOFA
A cell-permeable furoic acid compound that acts as a potent, reversible, and competitive inhibitor of acetyl-CoA carboxylase (ACC), a key enzyme involved in the fatty acid biosynthesis.
MilliporeSigma™ Calbiochem™ Urokinase Substrate III, Fluorogenic
Suitable for the quantitative direct fluorescent assay of urokinase.
MilliporeSigma™ Calbiochem™ Apicidin, Fusarium sp.
A potent, cell-permeable inhibitor of histone deacetylase (IC50 700 pM for parasitic histone deactetylase) that also exhibits antiprotozoal and potential anti-malarial properties.
MilliporeSigma™ Calbiochem™ SNX-482
A peptidyl toxin from venom of African tarantula, Hysterocrates gigas that acts as a high affinity, reversible blocker of Cav2.3 (α1E, R-type) channels (IC50 = 15-30 nM).
MilliporeSigma™ Calbiochem™ Sertraline Hydrochloride
A very potent uptake inhibitor highly selective for serotonin (Ki
MilliporeSigma™ Calbiochem™ Ghrelin Receptor Antagonist, JMV 2959
A 1, 2, 4-triazole derived compound that acts as a potent ghrelin receptor (GHS-R1a) antagonist (IC50 = 32nM in a binding assay, dissociation constant Kb =
MilliporeSigma™ Calbiochem™ MMP-2/MMP-3 Inhibitor III, PD166793
The MMP-2/MMP-3 Inhibitor III, PD166793, also referenced under CAS 199850-67-4, controls the biological activity of MMP-2/MMP-3. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
MilliporeSigma™ Calbiochem™ JNK Inhibitor II, Negative Control
The JNK Inhibitor II, Negative Control, also referenced under CAS 54642-23-8, controls the biological activity of JNK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ TNF-α Antagonist
The TNF-α Antagonist controls the biological activity of TNF-α.
MilliporeSigma™ Calbiochem™ NF-κB Activation Inhibitor
The NF-κB Activation Inhibitor, also referenced under CAS 545380-34-5, controls the biological activity of NF-κB. This small molecule/inhibitor is primarily used for Inflammation/Immunology applications.
MilliporeSigma™ Calbiochem™ AdaAhx3L3VS
A potent, covalent, cell-permeable, irreversible inhibitor of chymotrypsin-like (50-100 nM), trypsin-like (1-5 μM), and PGPH (0.5-1 μM) activities of the 20S proteasome.
MilliporeSigma™ Calbiochem™ p38 MAP Kinase Inhibitor VII, SD-169
The p38 MAP Kinase Inhibitor VII, SD-169, also referenced under CAS 1670-87-7, controls the biological activity of p38 MAP Kinase.