Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ FTY720
A cell-permeable aminopropanediol immunosuppressive agent that displays lymphocyte sequestration properties
MilliporeSigma™ Calbiochem™ Genistin
An isoflavone glycoside found in soy-based food products.
MilliporeSigma™ Calbiochem™ (+/-)-Atenolol
Selective β1 adrenergic blocking ag
MilliporeSigma™ Calbiochem™ Cytochalasin B, Dihydro-
Induces changes in cell morphology and motility with no effect on sugar transport.
MilliporeSigma™ Calbiochem™ Hypericin
Polycyclic dione that has anti-retroviral activity.
MilliporeSigma™ Calbiochem™ MKLP-2 Inhibitor, Paprotrain
The MKLP-2 Inhibitor, Paprotrain controls the biological activity of MKLP-2. This small molecule/inhibitor is primarily used for Cell Signaling applications.
MilliporeSigma™ Calbiochem™ PICK1 PDZ Domain Inhibitor, FSC231
The PICK1 PDZ Domain Inhibitor, FSC231 controls the biological activity of PICK1. This small molecule/inhibitor is primarily used for Neuroscience applications.
MilliporeSigma™ Calbiochem™ GSK-3 Inhibitor XVI
GSK-3 Inhibitor XVI - CAS 252917-06-9, is a cell-permeable, potent, ATP-competitive, and highly selective GSK-3 inhibitor (IC50 = 10 and 6.7 nM against GSK-3α and GSK-3β, respectively).
MilliporeSigma™ Calbiochem™ 4-Hydroxynonenal
4-Hydroxynonenal, CAS 75899-68-2, is a major aldehyde product formed by peroxidation of ω-6-unsaturated fatty acids that is regarded as a specific marker of lipid peroxidation.
MilliporeSigma™ Calbiochem™ Pravastatin, Sodium Salt
A water-soluble, competitive 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor that potently blocks in vivo cholesterol synthesis (Ki = ≈1 nM).
MilliporeSigma™ Calbiochem™ Phloretin
A cell-permeable inhibtor of protein kinase C (IC50 = 20-50 μM).
MilliporeSigma™ Calbiochem™ PP1 Analog II, 1NM-PP1
PP1 Analog II, CAS 221244-14-0, is a cell-permeable PP1 analog that acts as a potent, reversible, selective, ATP-competitive inhibitor of mutant over wild-type kinases.
MilliporeSigma™ Calbiochem™ PI 3-K/mTOR Inhibitor III, PKI-179
The PI 3-K/mTOR Inhibitor III, PKI-179, also referenced under CAS 1197160-28-3, controls the biological activity of PI 3-K/mTOR. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ JAK2 Inhibitor X, FLLL32
A cell permeable analog of curcumin that acts as a specific inhibitor of JAK2 (≈5 μM) and blocks STAT3 phosphorylation in MDA-MB-231 and PANC-1 cancer cells.
MilliporeSigma™ Calbiochem™ PIKfyve Inhibitor
The PIKfyve Inhibitor, also referenced under CAS 371942-69-7, controls the biological activity of PIKfyve. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.